HEPATIC CATABOLISM OF CHOLESTEROL
نویسندگان
چکیده
منابع مشابه
Regulation of hepatic glycine catabolism by glucagon.
Glucagon stimulates 14CO2 production from [1-14C] glycine by isolated rat hepatocytes. Maximal stimulation (70%) of decarboxylation of glycine by hepatocytes was achieved when the concentration of glucagon in the medium reached 10 nM; half-maximal stimulation occurred at a concentration of about 2 nM. A lag period of 10 min was observed before the stimulation could be measured. Inclusion of bet...
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Hepatic cholesterol metabolism was examined in 27 Swedish patients with cholesterol gallstone disease and in 13 patients free of gallstones operated for roentgenographically suspect polyps in the gallbladder. All 40 patients underwent cholecystectomy, and a liver biopsy and gallbladder bile were obtained at surgery. The cholesterol saturation of gallbladder bile was significantly higher in pati...
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Previous work from this labora tory has provided evidence tha t the synthesis of cholesterol is increased in ra ts subjected to ligation of the common bile duct (1). In t ravenous injection of the detergent t r i ton WR-1339 has been shown to produce a rise in serum cholesterol even more pronounced than tha t which follows bi l iary obstruct ion (2). Since there is some reason to believe tha t ...
متن کاملHepatic Cholesterol Metabolism
Although cholesterol is necessary to maintain cellular integrity and is an essential precursor for steroid hormones and bile acids, an elevated concentration of circulating cholesterol is a strong risk factor for cardiovascular diseases (CVDs), which accounts for ≈1 of every 3 deaths in the United States. In recognition of National Cholesterol Month, this article highlights recent studies publi...
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ژورنال
عنوان ژورنال: Pediatric Research
سال: 1986
ISSN: 0031-3998,1530-0447
DOI: 10.1203/00006450-198610000-00028